EPI 291: Seminar: Epidemiology -- Methodology

Fall Quarter, 2007

Guide to Course Material

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Course outline: (click below) 

Epidemiology 291, 2007 - Course Outline (10/31/07, pdf file)

Class photograph: (click below) 

Photos of EPI 291, 2007 class members (10/15/07, pdf file)

Assigned Reading:

The assigned readings by session are shown below (click ).  Please print the readings, read them before class, and bring them to class for discussion.  There will be no readings distributed in class. 

Session

Date

Printable Adobe PDF

Author, title, source, pages and date

PDF

1

10/01/07

Lopez et al. Chapter 1, Global Burden of Disease and Risk Factors, 2006, pp. 1-13.

Murray CJ et al. Global burden of disease 2005: call for collaborators. Lancet 370(9582), 109-10, 2007.

2

10/08/07

Mathers et al. Chapter 3, Global Burden of Disease and Risk Factors, 2006. pp. 45-93 and pp. 234-240.

 

- pp. 45-58

- pp. 59-72

- pp. 73-86

- pp. 87-93 and 234-240

3

10/15/07

Mathers et al. Chapter 5, Global Burden of Disease and Risk Factors, 2006, pp. 399-426.

- pp. 399-404

- pp. 405-410

- pp. 411-415

- pp. 416-426

4

10/22/07

Mathers et al. Chapter 5, Global Burden of Disease and Risk Factors, 2006, pp. 399-426. (continued)

 

5

10/29/07

McKenna et al. Assessing the burden of disease in the United States using disability-adjusted life years. American J Preventive Medicine 28(5), 415-23, 2005.

Michaud CM, McKenna MT, Begg S, Tomijima N, Majmudar M, Bulzacchelli MT, Ebrahim S, Ezzati M, Salomon JA, Kreiser JG, Hogan M, Murray CJ. The burden of disease and injury in the United States 1996. Population Health Metrics 4, 1-49, 2006 (for Additional Files 1-5, click in Supplemental Material below)

6

11/05/07

Anand S and Hanson K. Disability-adjusted life years: a critical review. Journal of Health Economics 16, 685-702, 1997. 

7

11/12/07

Veterans Day Holiday

--

8

11/19/07

Steenland K and Armstrong B. An Overview of Methods for Calculating the Burden of Disease Due to Specific Risk Factors. Epidemiology 17(5), 512-9, 2006.

9

11/26/07

Group D (#3)

 

Group C (#2)  

10

12/03/07

Group A (#7)

 

Group B (#10)  

 

References for Group Presentations (select one):

Once formed, each group must discuss their selection with Professor Frerichs.  No two groups can select the same article.

Group A: (10/15/07): Sara Chacko, Brian Chen, Tanmay Mahapatra, and Ryan Murphy; Article #7.

Group B: (10/17/07): Muhammad Farid, Yingbo Ma and Benjamin Tang; Article #10

Group C: (10/22/07): Janet Cheng, Ai-Ying Lin, Nguyen Nguyen Binh, Sheena Sullivan; Article #2

Group D: (10/22/07): Leona Bessonova, Justine Harbison, Jodie Katon, Sona Oksuzyan; Article #3

1.  Abdalla SI, Malik EM, Ali KM. The burden of malaria in Sudan: incidence, mortality and disability-adjusted-life-years. Malaria Journal 6(1):97, 2007. [Epub ahead of print]

2. Anderson KB, Chunsuttiwat S, Nisalak A, Mammen MP, Libraty DH, Rothman AL, Green S, Vaughn DW, Ennis FA, Endy TP. Burden of symptomatic dengue infection in children at primary school in Thailand: a prospective study. Lancet 369(9571),1452-9, 2007.

3. Bjegovic V, Terzic Z, Marinkovic J, Lalic N, Sipetic S, Laaser U. The burden of type 2 diabetes in Serbia and the cost-effectiveness of its management. European J Health Economics 8(2), 97-103, 2007.

4. Cadilhac DA, Carter RC, Thrift AG, Dewey HM. Why invest in a national public health program for stroke? An example using Australian data to estimate the potential benefits and cost implications. Health Policy 83(2-3), 287-94, 2007.

5. Gureje O, Chisholm D, Kola L, Lasebikan V, Saxena S. Cost-effectiveness of an essential mental health intervention package in Nigeria. World Psychiatry 6(1), 42-8, 2007.

6. Lai T, Habicht J, Reinap M, Chisholm D, Baltussen R. Costs, health effects and cost-effectiveness of alcohol and tobacco control strategies in Estonia. Health Policy. 2007 Mar 31; [Epub ahead of print, 14 pages]

7.  Pitter C, Kahn JG, Marseille E, Lule JR, McFarland DA, Ekwaru JP, Bunnell R, Coutinho A, Mermin J. Cost-effectiveness of cotrimoxazole prophylaxis among persons with HIV in Uganda. J Acquired Immune Deficiency Syndromes 44(3), 336-43, 2007.

8.  Polinder S, Meerding WJ, Mulder S, Petridou E, van Beeck E and EUROCOST Reference Group. Assessing the burden of injury in six European countries. Bulletin of the World Health Organization 85(1), 27-34, 2007.

9.  Schackman BR, Neukermans CP, Fontain SN, Nolte C, Joseph P, Pape JW, Fitzgerald DW. Cost-effectiveness of rapid syphilis screening in prenatal HIV testing programs in Haiti. PloS Medicine 4(5), 937-47, 2007.

10. Yoon SJ, Bae SC, Lee SI, Chang H, Jo HS, Sung JH, Park JH, Lee JY, Shin Y. Measuring the burden of disease in Korea. Journal of Korean Medical Science 22(3), 518-23, 2007.

Session Powerpoint Presentations:

The slide notes as PDF files will be available before the lectures or discussions (click ) and Powerpoint presentations (click ) will be available after the lectures or discussions. 

Session Date Viewable Powerpoint Presentation PDF

PPT

Topic
1 10/1/07 GBD1, GBD2, Deaths, YLL, YDL, DALYs

 

 
2 10/8/07 Calculation of YLL and YDL issues  
3 10/15/07 Sensitivity and Uncertainty analysis (1)  
4 10/22/07 Sensitivity and Uncertainty analysis (2)  
5 10/29/07 Derivation of DALYs in USA  
6 11/5/07 Critique of DALYs  
7 11/12/07 Veterans Day Holiday   -- --
8 11/19/07 Attributable fractions and DALYs  
9 11/26/07 Student Group D (Article #3)  
Student Group C (Article #2)  
10 12/03/07 Student Group A (Article #7)  
Student Group B (Article #10)  

Supplemental Material Included in Class:

Various articles that appear in the literature during the course will be posted (click ). 

Session Date Printable Adobe PDF XLS

PDF

Topic
1 10/1/07 Lopez, A.D., Mathers, C.D., et al. Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet 367, 1747-57, 2006

 

 
5 10/29/07

Additional File 1. Global burden of disease methodology: summary overview. A summary overview of GBD methods.

   

Additional File 2. Data sources and methods for developing estimates for the incidence, mortality, prevalence, and duration of selected conditions for estimation of YLD in the United States. A detailed presentation of analytic methods, data sources, and data sets used to develop estimates for major causes of diseases and injuries.

   

Additional File 3. US burden of disease study classification system for diseases and injuries. The detailed list of causes selected for the USBODI.

   

Additional File 4. US burden of disease – Detailed tabulations of deaths, YLL, YLD and DALYs. Detailed tabulations of deaths, YLL, YLD and DALYs for the 73 causes included in the USBODI by age, gender and race.

   

Additional File 5. Epidemiological estimates. Detailed incidence by age, sex and race by disease and sequelae, included in the USBODI.

   

Melse, JM et al. A national burden of Disease calculation: Dutch disability-adjusted life years. American J Public Health 90(8), 1241-1247, 2000.

   
8 11/19/07 Hartge, P. Estimating the burden of disease and the benefits of prevention. Epidemiology 17(5), 498-499, 2006