200A. Epidemiology I (6)
Lecture and discussion, four hours. Preparation: one full biological sciences course. Requisite: Biostatistics 100A (may be taken concurrently). Not open for credit to students with credit for course 100. Basic concepts, principles, and methods of chronic and infectious disease epidemiology, including study designs and basic measures of disease frequency and exposure-disease associations.
Dr. Olsen

222. Arthropods as Vectors of Human Diseases (4)
Lecture, four hours. Requisites: courses 100 or 200, 220. Comprehensive overview of morphology, systematics, natural history, host/vector/pathogen relationships, and spectrum of diseases carried by arthropods for graduate students, public health professionals, and medical doctors seeking information on global prevalence of arthropod-borne diseases. Letter grading.
Dr. Berlin

223. Biology and Ecology of Human Parasitic Diseases (4)
Lecture, four hours. Information on all aspects of parasitic organisms causing human disease, including their morphology, biology, means of diagnosis, and diseases they cause. From epidemiological perspective, special emphasis on way in which parasites maintain themselves in nature, and manner in which organisms are transmitted to people. Letter grading.

224. Zoonotic Diseases and Public's Health (4)

Lecture, four hours. Examination of wide variety of infectious disease agents (viruses, bacteria, and protozoan and helminth parasites) causing diseases in individuals and populations. Emphasis on how these diseases exist in natural environment, how they are transmitted from animals to humans, and methods for their prevention and control. Letter grading.

Dr. Ash

225. Role of Public Health Laboratory in Disease Control (2)
Lecture, two hours. Requisite: course 100 or 200, 220. Role of public health laboratory is to support testing needs of the programs.  To successfully fulfill this role, laboratory must provide information based on most sensitive and specific technologies available.  Coverage of common infectious disease agents of public health importance and definition of impact of m9lecular biology on disease detection and epidemiology in modern public health laboratory.  S/U or letter grading.
Dr. Harvey

226. Public Health Responses to Bioterrorism (4)

Lecture, four hours. Requisite: course 220 or 221. Mitigation of bioterrorism falls outside traditional public health programs and public health graduate education. Because of seriousness of such threats, it is important that individuals trained in public health understand problems and responses. Letter grading.

Dr. Kim-Farley

227. AIDS: A Major Public Health Challenge (4)
Lecture, four hours. Requisites: course 100 or 200, Biostatistics 100A or 110A. Presentation of epidemiologic, biologic, psychological, and clinical characteristics of AIDS and HIV_1 infection. Discussion of policy implications and intervention strategies. S/U or letter grading. 
Dr. Detels

M228. Biology of HIV (4) 
(Same as Microbiology and Immunology M275.)
Lecture, three hours. Preparation: two biology courses. Requisites: course 100, Biostatistics 100A. Overview of virologic and immunologic aspects of HIV disease for epidemiology or other health disciplines. Brief discussion of clinical manifestations and biosafety in the laboratory. Letter grading. 
Dr. Jamieson

229. Foodborne Illnesses (2)

Lecture, two hours. Requisites: course 100 or 200, Biostatistics 100A. Food poisoning is a significant cause of morbidity and mortality in both developing and developed world. Examination of etiologic agents of food poisoning and factors specific to foods that allow them to become agents of disease transmission. S/U or letter grading.

230. Epidemiology of Sexually Transmitted Diseases (4)
Lecture, four hours. Requisite: course 100 or 200. Sexually transmitted diseases; medical/biological aspects, epidemiology and control in developed and developing countries. S/U or letter grading. 
Dr. Visscher

240. Cardiovascular Epidemiology (2)
Lecture, two hours. Topics include definition, pathogenesis, descriptive epidemiology, magnitude of risk factors, strategies for prevention, lipoprotein metabolism, and epidemiology of diabetes, hypertension, and chronic lung disease. Letter grading. 
Dr. Wong

242. Cancer Epidemiology (4)
Lecture, four hours. Requisite: course 100 or 200. Introduction to basic concepts of cancer and molecular and genetic epidemiology. Review of current epidemiologic research in cancer in recent medical and epidemiological literature. Research proposal on a cancer-related topic required. S/U or letter grading.
Dr. Zhang

243. Molecular Epidemiology of Cancer (4)

Lecture, four hours. Requisite: course 242 or 295. Introduction to basic concepts and methodology of molecular epidemiology of cancer and review of current molecular epidemiologic research of cancer in recent medical and epidemiological literature. S/U or letter grading.

Dr. Zhang

244. Research Methods in Cancer Epidemiology (2)

Lecture, two hours. Requisites: courses 100 and/or 200, Biostatistics 100A. Biologic, quantitative, philosophical, and administrative considerations in epidemiologic cancer research. Hypothesis specification and choice of study design. Uses of descriptive epidemiology, cohort studies, case control studies. Clustering, screening, and cancer control. Means of identifying subjects and controls. Design of instruments. Sources of bias and confounding. S/U or letter grading.

Dr. Zhang

246. Epidemiology of Aging (2)
Lecture, two hours. Requisite: course 100 or 200. Epidemiologic methods of estimating present and future burdens of aging: morbidity, disability, and dependency. Epidemiology of major disabling conditions affecting the elderly. Evaluation of possible intervention strategies. Methodological issues in geriatric epidemiology. S/U or letter grading. 
Dr. Malmgren

247. Epidemiology of Injuries in the Elderly (2)
Lecture, two hours. Requisite: course 100. Description of frequency of, risk factors for, and possibilities of preventing injuries in the elderly populations. Comparison of injury outcomes (morbidity and mortality) younger vs. older populations. Emphasis on methodological issues of studying elderly people. S/U or letter grading. 
Dr. Malmgren

248. Psychiatric Epidemiology (4)
Lecture, four hours. Requisite: course 100 or 200. Introduction to basic concepts and research methods in psychiatric epidemiology. Topics include case definition, study design, instrumentation, and epidemiology of selected psychiatric disorders. Letter grading. 
Dr. Cochran

249. Genetic Epidemiology I (2)

Lecture, two hours. Preparation: at least one course in epidemiology, biostatistics, and genetics. Basic concepts in emerging field of genetic epidemiology, with principal focus on genetic study of complex diseases, determining genetic contributions to disease, identifying genes, and characterizing their main effects and interactions with environmental factors. Letter grading.

251. Epidemiology of Nonintentional Injuries (4)
Lecture, three hours; discussion, two hours. Requisites: course 100 or 200, Biostatistics 100A. Pertinent epidemiology methods for study of nonintentional trauma, including that from motor vehicle crashes occupational exposures, falls, and other major external causes, which focus on research approaches data sources, analytical techniques. Substantive findings on related subproblem areas presented for critical review. Letter grading. 
Dr. Kraus

252. Epidemiology of Assault, Homicide, and Suicide (2)
Lecture, two hours; discussion, one hour Requisite: course 100 or 200. Presentation and evaluation of epidemiologic research approaches to study of violent injury, including description of incidence, study design, risk factor analysis, and control evaluation. S/U or letter grading. 
 

253. Acute Traumatic and Chronic Repetitive lnjuries from Work-Related Exposures (2)
Lecture, two hours; discussion, one hour. Requisites: course 100, Biostatistics 100A. Lectures and discussions on magnitude, scope, research approaches, and intervention strategies for work-related acute traumatic and chronic repetitive (musculoskeletal) injuries. Emphasis on injury research methods for all external causes of injury, utilizing epidemiology for high-risk group and risk-factor identification and injury prevention. S/U or letter grading. 
 

M255. Keeping Children Safe: Causes and Prevention of Pediatric Injuries (2) 
(Same as Community Health Sciences M255.)
Lecture, two hours.  Injuries have been leading killer of children in the U.S. for decades. Children have specific risk factor for injuries, many of which are preventable. Presentation of approaches to research and prevention of pediatric injuries. Letter grading. 
Dr. Limbos

257. Nutritional Epidemiology (2)

Lecture, three hours. Preparation: at least one introductory epidemiology course. Introduction to study of foods and nutrients in causation or prevention of diseases. Discussion of methods for collecting data on diet, study design and analysis, and specific research studies about nutritional influences on disease. S/U or letter grading.

Dr. Liu

258. Molecular Epidemiology of Diabetes and Obesity (4)

Lecture or Laboratory, four hours. This course surveys the entire landscape of the nutritional, biochemical, and genetic aspects of obesity (overweight, obesity, and extreme obesity), diabetes (type 1 and type 2), and their micro- and macro-vascular complications. The descriptive and analytical epidemiology of these seemingly distinct yet clearly clustered disorders including the so-called metabolic syndrome will be reviewed comprehensively and in-depth. It is hoped that through studying the distributions and determinants of these highly prevalent disorders in Westernized populations, students will appreciate how and why these epidemics of our time occurred. Through case studies, the students will learn the process of generating etiologic hypotheses that can be tested using a myriad of modern molecular epidemiologic methods. Techniques and principal of molecular genetics relevant to epidemiologic studies will be reviewed and demonstrated. Real data sets which include both genotype and phenotype information will be analyzed with emphasis placed on the examination of various gene/environment interactions. International comparison of prevalent data in different social contexts will also be reviewed, so that the strategies for prevention by either changing our cultures or natures can be appreciated and debated with a better understanding of the related issues confronted by public health and medical professionals.
Letter grading.

Dr. Liu

259. Disaster Epidemiology (2)
Lecture, two hours. Requisites: course 100 or 200, Community Health Sciences 295. Introduction to epidemiologic methodology to study disasters and their health outcomes including surveillance, loss estimation, risk factor as assessment, intervention, and evaluation. Letter grading. 

260. Environmental Epidemiology (2)
Lecture, one hour; discussion, one hour. Requisite: course 100 or 200. Methodological problems and approaches of epidemiology for assessing health impact of major types of environmental exposure. Letter grading. 
Dr. Ritz

261. Occupational Epidemiology (4)
Lecture, two hours; discussion, two hours. Requisite: course 100 or 200. Methodological considerations, approaches and limitations in epidemiological studies of occupational groups and environments. S/U or letter grading. 
Dr. Ritz

262. Seminar: Environmental and Occupational Cancer Epidemiology (2)
Seminar, two hours. Requisite: course 100 or 200. Discussion of examples of recent epidemiologic studies, with focus on environmental and occupational exposures, especially in areas where controversies have arisen such as for electromagnetic fields and childhood leukemia, and bladder cancer and trihalomethanes levels of drinking water. S/U or letter grading. 
Dr. Ritz

263. Exposure Assessment in Occupational and Environmental Epidemiology (2)

Lecture, two hours. Requisite: course 100 or 200. Exposure assessment is often most challenging aspect of epidemiologic studies of occupational and environmental hazards. Focus on integration of industrial hygiene principles and epidemiologic methods to improve exposure assessment protocols and exposure analyses for occupational/environmental health studies. S/U or letter grading.

265. Epidemiology Methods in Occupational and Environmental Health (2)

Lecture, two hours. Introduction to epidemiology methods applied to evaluation of human health consequences of occupational and environmental hazards, including study design, exposure assessment, and statistical techniques commonly encountered in research focused on assessing adverse health effects resulting from occupational and environmental exposures. Topics include clusters, meta-analysis, risk assessment, and policy development. Illustrated by case studies, with focus on techniques to critically evaluate and interpret current literature. Letter grading.

267. Methodologic Issues in Reproductive Epidemiology (2) Seminar, two hours. General discussion of methodologic issues important to epidemiologic studies of reproductive outcomes, including fertility, low birth weight, prematurity, birth defects, pregnancy loss, and perinatal mortality. Approaches to study design and exposure assessment and identification of potential sources of bias illustrated through review of recent studies published in literature and with particular focus on occupational and environmental exposures and birth cohorts. S/U or letter grading.

268. Introduction to Pharmacoepidemiology (2)
Lecture, two hours. Requisite: course 200. Pharmacoepidemiology is application of epidemiologic knowledge, reasoning, and methods to study of effects and uses of drugs. Survey of contemporary roles of pharmacoepidemiology in drug development and public health, with historical background of its evolution and projections of future prospects. S/U or letter grading. 
Dr. Ackerman

270. Epidemiology and Health Policy (2)
Lecture, two hours. Requisites: courses 100 or 201A-201B, Biostatistics 100B or 110B, Health Services 100. Application of epidemiologic methods and findings in health services research, population health planning, and health policy to provide framework for integrating causal inference with decision making. Emphasis on conceptual and methodologic issues confronting researchers, clinicians, planners, administrators, and legislators. S/U or letter grading.

290. Seminar: Epidemiology of Infectious and Tropical Disease (2)
Seminar, two hours. Review of research on specific diseases of public health importance. May be repeated for credit. S/U or letter grading.

291. Seminar: Epidemiology - Methodology (2)
Seminar, two hours. Requisite: course 100 or 200. Review of current epidemiologic research contained in recent medical literature. May be repeated for credit. S/U or letter grading.

Dr. Frerichs

292. Advanced Seminar: Epidemiology (2)
Seminar, two hours. Requisite: course 2018. Current research in epidemiology. May be repeated for credit. S/U grading.

293. International HIV/AIDS Seminar (2)
Seminar, two hours. Ongoing discussion of worldwide pandemic of HIV/AIDS, with emphasis on problems of surveillance, reporting, and intervention. Discussion of recent literature. Presentations by fellows from other countries. S/U grading. 
Dr. Detels

294. Epidemiology and Policy of Occupational and Environmental Health Issues (2)
Seminar, two hours. Requisite: course 100 or any other epidemiology course. Introduction to demands that go beyond "pure science," with focus on issues such as risk communication, potential influence (and ethics) of oversight panels and external review groups on presenting results and conclusions, and interest of government agencies. S/U grading. 
Dr. Ritz

295. Seminar: Epidemiology - Cancer (2)
Seminar, two hours. Requisite: course 100 or 200. Introduction of basic concepts of cancer epidemiology and review of current epidemiological research in cancer in recent medical and epidemiological literature. May be repeated for credit. S/U or letter grading. 
Dr. Zhang

400. Field Studies in Epidemiology (4)
Field work, to be arranged. Field observation and studies in selected community organizations for health promotion or medical care. Students must file field placement and program training documentation on form available from Student Affairs Office. May not be applied toward MS. minimum course requirement; four units may be applied toward 44-unit minimum total required for MPH degree. Letter grading.

401. Database Theory and Practical Applications in Injury Epidemiology (2)
Lecture, two hours. Requisite: course 201A. Exploration of theory and practical strategies for database construction and manipulation, selection, and use of desktop-computing database applications using a variety of examples from epidemiological research. Letter grading. 
Dr. McArthur

402. Advanced Data Analysis in Occupational and Environmental Epidemiology (4)
Lecture, two hours; laboratory, two hours. Preparation: one data management course. Requisites: courses 201A-201B, or 201A and 261. Development of strategies for analyzing data in occupational and environmental settings. Use of multivariate data analysis techniques typically used in occupational cohort studies, nested case-control studies, and ecologic studies in environmental epidemiology. S/U or letter grading. 
Dr. Ritz

M403. Computer Management and Analysis of Health Data Using SAS

Formerly numbered M403B.) (Same as Biostatistics M403B.) Lecture, two hours; laboratory, two hours. Requisites: Biostatistics 100A, 100B (100B may be taken concurrently). Introduction to practical issues in management and analysis of health data using SAS programming language. Cross-sectional and longitudinal population-based data sets to be used throughout to illustrate principles of data management and analysis for addressing biomedical and health-related hypotheses. Letter grading.

406. Preparing for a Smallpox or Other Bioterrorist Event (2)
Lecture, two hours. A major current public health issue is the massive effort to prepare for possible bioterrorist events. This class focuses on the practical application of the principles of epidemiology and public health in preparing for a smallpox or other bioterrorist event. Letter grading.

Dr. Kim-Farley

410. Management of Epidemiologic Data (2)
Lecture, two hours. Requisites: course 100, Biostatistics 100 (one course may be taken concurrently with consent of instructor). Concepts, collection, and management of data, with particular emphasis on databases in chronic infectious diseases, Introduction to personal computers and appropriate software for epidemiologic studies. S/U or letter grading. 
Dr. Cochran

411. Research Resources in Epidemiology (2)
Lecture, one hour; discussion, one hour. Instruction and practical experience in use of varied bibliographic aids and sources of information, building of reference tiles, and presentation of research findings for publication. S/U or letter grading. 
Dr. Smith

412. Public Health Surveillance (2)
Lecture, two hours. Requisites: course 100 or 200, Biostatistics 100A. Overview of public health surveillance methodology, including (1) design, implementation, and evaluation of surveillance systems, (2) analysis and interpretation of surveillance data, and (3) application of surveillance methods to specific health-related outcomes. Letter grading. 
Dr. Simon

414. Practical Epidemiologic Investigations (2 to 4)
Lecture, one to two hours: laboratory, one to two hours. Requisite: course 100 or 200. Practical approaches to epidemic investigations presented through problem sets based on actual outbreaks. Data collection, analysis, and written presentation of findings. S/U or letter grading.
Dr. Strassburg 

415. Epidemiology for Developing Countries (4)
Lecture, four hours. Requisite: courses 100 and/or 200, Biostatistics 100A.  Practical use of epidemiology, public policy, microcomputers, and spreadsheet models for estimating morbidity and mortality, developing intervention or prevention strategies, and setting program priorities in Third World settings.  Letter grading. 
Drs. Frerichs and Rimoin (Winter)

417. Injury Prevention Strategies and Countermeasures (2) 
(Formerly numbered M417.)
Lecture, two hours. Requisite: course 100. Lectures with discussion on injury prevention strategies and countermeasures, including critical review of effectiveness in the public health context. Emphasis on major public health injury problems from assaultive, self-inflicted, or unintentional causes. S/U or letter grading. 
Dr. Kraus