Epidemiology 242 - Cancer Epidemiology
Professor Zuo-Feng Zhang
Mondays and Wednesdays 10-11:50 A.M.
Rm. 71-257 CHS
Fall 2007
Week 1
10/01/07 - Introduction: Course outline and Requirements
Lecture Slides
Lecture 1-1: Cancer Epidemiology: Introduction (ppt)
10/03/07 ¨C Cancer as a Major Health Problem and Individual Cancer Risk Assessment
Lecture Slides
Lecture 1-2: Cancer as Major Health Problem (ppt)
Reading
Cancer epidemiology in the last century and the next decade (pdf)
Environmental and Heritable Factors in the Causation of Cancer (pdf)
Week 2
10/08/07 ¨C Pathological Basis of Cancer
Lecture Slides
Lecture 2-1: Pathological Basis of Cancer (ppt)
Reading
10/10/07 ¨C Descriptive Epidemiology in Human Cancer
Lecture Slides
Lecture 2-2-1: World Burden of Cancer (ppt)
Lecture 2-2-2: World Projections (ppt)
Lecture 2-2-3: US Cancer Burden (ppt)
Reading
Global Cancer Statistics, 2002 (pdf)
Cancer Statistics, 2007 (pdf)
Week 3
10/15/07 ¨C Stages in Neoplastic Development
Lecture Slides
Lecture 3-1: Stages in Neoplastic Development (ppt)
Reading
Stages in Neoplastic Development (pdf)
Chemical-Induced DNA Damage and Human Cancer Risk (pdf)
Nature and Nurture - Lessons from Chemical Carcinogenesis (pdf)
10/17/07 - Hypothesis Generating and Testing and Study Design in Cancer Epidemiology
Lecture Slides
Lecture 3-2a: Hypothesis Generating and Testing (ppt)
Lecture 3-2: Study Designs in Cancer Epidemiology (ppt)
Reading
Concepts in Cancer Epidemiology and Etiology (pdf)
11th Report on Carcinogens (html)
Week 4
10/22/07- Molecular Epidemiology
Lecture Slides
Lecture 4-1: Cancer Molecular Epidemiology (ppt)
Reading
Association studies for finding cancer-susceptibility genetic variants (pdf)
The search for low-penetrance cancer susceptibility alleles (pdf)
Individual susceptibility to carcinogens (pdf)
10/24/07- Nutritional Epidemiology
Lecture Slides
Lecture 4-2: Nutrition and Cancer (ppt)
Epimonitor- October 2007 (pdf)
Week 5
10/29/07- Smoking and Cancer
Lecture Slides
Lecture 5-1: Cigarette Smoking and Cancer Risk (ppt)
10/31/07- Pre-malignant Lesion and Chemoprevention
Lecture Slides
Lecture 5-2: Cancer Chemoprevention & Surrogate End Point Markers (ppt)
Lecture 5-2b: Cancer Chemoprevention & Biomarkers (ppt)
Reading
Chemoprevention of Cancer (pdf)
11/1/07- Genetic Epidemiology Seminar: Mendelian randomization: Can genetics help us identify modifiable causes of disease?
Week 6
11/5/07- Mid-term Examination
11/7/07- Infection and Cancer
Lecture Slides
Updated: Lecture 11/7/07: Infection and Cancer by Dr. Goldstein (ppt)
Lecture 6-2b: Infection and Cancer (ppt)
Reading
Infections and immune factors in cancer: the role of epidemiology (pdf)
Viruses, chemicals and co-carcinogenesis (pdf)
Week 7
11/14/07- University Holiday
11/16/07- Alcohol and Cancer
Lecture Slides
Lecture 7-1: Alcohol and Cancer (ppt)
Reading
Chapter 15: Alcohol (Textbook)
Week 8
11/19/07- Obesity and Cancer Risk
Lecture Slides
Lecture 8-1: Obesity and Cancer (ppt)
Reading
Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms (pdf)
11/21/07- Occupation and Cancer
Lecture Slides
Lecture 8-2: Environmental, Occupational Exposures and Cancer (ppt)
Reading
Epidemiology of environmental and occupational cancer (pdf)
Week 9
11/26/07- Epidemiology of Breast Cancer
Lecture Slides
Lecture 9-1: Epidemiology of Breast Cancer (ppt)
Lecture 9-2: Environmental Exposure and Cancer (ppt)
Reading
Prevention of cancers of the breast, endometrium and ovary (pdf)
11/28/07- Epidemiology of Prostate Cancer
Lecture Slides
Lecture 9-2: Epidemiology of Prostate Cancer (ppt)
Week 10
12/3/07- Epidemiology of Colorectal Cancer
Lecture Slides
Lecture 10-1: Colorectal Cancer (ppt)
12/5/07- Cancer Epidemiology Summary
Lecture Slides
Lecture 10-2: Summary of Cancer Epidemiology (ppt)
Week 11
Final Examination