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METHODOLOGY
Luman ET, Worku A, Berhane Y, Martin R, Cairns L.
Comparison of two survey methodologies to assess vaccination coverage.
International Journal of Epidemiology 36(3), 633-41, 2007.
BACKGROUND: Measuring vaccination coverage permits
evaluation and appropriate targeting of vaccination services. The cluster survey
methodology developed by the World Health Organization, known as the 'Expanded
Program on Immunization (EPI) methodology', has been used worldwide to assess
vaccination coverage; however, the manner in which households are selected has
been criticized by survey statisticians as lacking methodological rigor and
introducing bias. METHODS: Thirty clusters were selected from an urban (Ambo)
and a rural (Yaya-Gulelena D/Libanos) district of Ethiopia; vaccination coverage
surveys were conducted using both EPI sampling and systematic random sampling (SystRS)
of households. Chi-square tests were used to compare results from the two
methodologies; relative feasibility of the sampling methodologies was assessed.
RESULTS: Vaccination coverage from a recent measles campaign among children aged
6 months through 14 years was high: 95% in Ambo (both methodologies), 91 and 94%
(SystRS and EPI sampling, respectively, P-value = 0.05) in Yaya-Gulelena D/Libanos.
Coverage with routine vaccinations among children aged 12-23 months was <20% in
both districts; in Ambo, EPI sampling produced consistently higher estimates of
routine coverage than SystRS. Differences between the two methods were found in
demographic characteristics and recent health histories. Average time required
to complete a cluster was 16 h for EPI sampling and 17 h for SystRS; total cost
was equivalent. Interviewers reported slightly more difficulty conducting SystRS.
CONCLUSIONS: Because of the methodological advantages and demonstrated
feasibility, SystRS would be preferred to EPI sampling in most situations.
Validating results in additional settings is recommended.
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