The 14th and 15th cholera cases in 1848 occurred in Spitalfields, a community due north of the Tower of London. The Spitalfields Market (in red) is identified as a landmark, not the exact location of the two vaguely-described cases.

Source: Cross, J. Cross's New Plan Of London 1850, J. Cross, 18, Holborn Hill, opposite Furnivals Inn, January 1, 1850.  View Cross map at: MAPCO: Map And Plan Collection Online