*Anne M. Andrews, Ph.D.
+* Jesus A. Araujo, MD, Ph.D.
Judith Berliner, Ph.D.,
+* Jeff Bronstein, M.D., Ph.D.
Gautam Chaudhuri, M.D.
+* Marie-Francoise Chesselet, Ph.D.
Catherine Clarke, Ph.D.
* Michael Collins, Ph.D
Curtis Eckhert, Ph.D.
Richard Gatti, Ph.D.
* Hilary Godwin, Ph.D.
+* Oliver Hankinson, Ph.D.
Louis J. Ignarro, Ph.D.
+* David Krantz, Ph.D
William McBride, Ph.D
William Melega, Ph.D.
* Sabeeha Merchant, Ph.D.
+ Jeffrey H. Miller, Ph.D.
+ Andre Nel, MD, Ph.D.
Frank Pajonk, M.D., Ph.D
Suzanne E. Paulson, Ph.D.
+* Beate Ritz, MD., Ph.D.
* Wendie Robbins, Ph.D.
* Michael Roth, M.D
+* Robert Schiestl, Ph.D.
Joan S. Valentine, Ph.D.
Xia Yang, Ph.D.
Zuo-Feng Zhang, Ph.D.
+* Jesus A. Araujo, MD, Ph.D.
Judith Berliner, Ph.D.,
+* Jeff Bronstein, M.D., Ph.D.
Gautam Chaudhuri, M.D.
+* Marie-Francoise Chesselet, Ph.D.
Catherine Clarke, Ph.D.
* Michael Collins, Ph.D
Curtis Eckhert, Ph.D.
Richard Gatti, Ph.D.
* Hilary Godwin, Ph.D.
+* Oliver Hankinson, Ph.D.
Louis J. Ignarro, Ph.D.
+* David Krantz, Ph.D
William McBride, Ph.D
William Melega, Ph.D.
* Sabeeha Merchant, Ph.D.
+ Jeffrey H. Miller, Ph.D.
+ Andre Nel, MD, Ph.D.
Frank Pajonk, M.D., Ph.D
Suzanne E. Paulson, Ph.D.
+* Beate Ritz, MD., Ph.D.
* Wendie Robbins, Ph.D.
* Michael Roth, M.D
+* Robert Schiestl, Ph.D.
Joan S. Valentine, Ph.D.
Xia Yang, Ph.D.
Zuo-Feng Zhang, Ph.D.
* indicates professors available for advising
+ indicates faculty members of the UCLA NIEHS training grant in "Molecular Toxicology"
*Anne M. Andrews, Ph.D.
Psychology and Biobehavioral Science - Full BiographyDr. Andrews' research is centered on the investigation of therapeutics, drugs of abuse, neurotoxins, and environmental factors to probe the molecular basis of serotonin system function associated with the etiology and treatment of mood and anxiety disorders.
+* Jesus A. Araujo, MD, Ph.D.
Medicine, Environmental Cardiology - Full BiographyDr. Araujo's research program focuses on the study of genetic and environmental factors involved in vascular oxidative stress and atherosclerosis, including the dissection of molecular mechanisms responsible for the cardiovascular toxicity of air pollutants.
Judith Berliner, Ph.D.,
Pathology and Laboratory Medicine - Full BiographyDr. Berliner's research deals with the events mediating chronic inflammatory processes such as those that occur in atherosclerosis, cancer, and rheumatoid arthritis.
+* Jeff Bronstein, M.D., Ph.D.
Neurology - Full BiographyJeff Bronstein received his bachelor's degree from the University of California, Berkeley and M.D. and Ph.D. from UCLA as a recipient of the Medical Scientist Training Program Award. He completed a residency in Neurology and fellowship training in Movement Disorders at UCLA and at Queens Square in London. Dr. Bronstein also completed a postdoctoral fellowship in molecular biology before being appointed an Assistant Professor of Neurology in 1994 and Director of the Movement Disorders Program in 1996 at UCLA. His clinical interests include the management of Parkinson's disease (PD) and other movement disorders, surgical treatment of PD, and developing new therapies for patients. Dr. Bronstein's research interests include the study of the causes of PD (environmental and genetic) using cell and zebrafish models as well as population-based studies. His research is supported by the NIH, Veteran Administration, and private foundations. Dr. Bronstein is the Principle Investigator of one of 6 National Parkinson's Disease Centers (PADRECC) at the Veterans Administration Medical Center, is a project PI of the UCLA Collaborative Center for Parkinson's Disease Environmental Research (CCPDER) funded by the NIEHS and is an Investigator in the UCLA Udall Center.
Gautam Chaudhuri, M.D.
OB/GYN and Pharmacology - Full BiographyDr. Chaudhuri's research focuses on the mechanism by which estradiol and nitric oxide modulate various physiological functions and the signal transduction pathways involved.
+* Marie-Francoise Chesselet, Ph.D.
Chair-Neurobiology; Charles H. Markham Professor, Neurology - Full BiographyDr. Chesselet's laboratory explores molecular mechanisms leading to neurodegenerative diseases of the basal ganglia, such as Huntington's disease and Parkinson's disease She is interested in the mechanisms by which environmental toxins, specifically agricultural pesticides, may interact with genetic risk factors to cause increased risks of Parkinson's disease. This work is primarily conducted in mouse models of Parkinson's disease but also involves neuronal cultures.
Catherine Clarke, Ph.D.
Chemistry and Biochemistry - Full BiographyCoenzyme Q (also known as ubiquinone or Q) is a lipid component of cellular membranes that plays an essential role in the respiratory electron transport chain. Dr. Clarke studies the biosynthesis, regulation, and function of Q in the yeast Saccharomyces cerevisiae.
* Michael Collins, Ph.D
Environmental Health Sciences - Full BiographyResearch in Dr. Collins' laboratory is concerned with aspects of developmental toxicology or teratology.
Curtis Eckhert, Ph.D.
Environmental Health Sciences - Full BiographyDr. Eckhert's research program is concerned with elucidating the molecular basis of boron essentiality and toxicity in humans and animals.
Richard Gatti, Ph.D.
Pathology and Labortory Medicine - Full BiographyDr. Gatti's research focuses on ataxia-telangiectasia and other chromosomal instability disorders. The lab specializes in diagnostic assays, mutation screening and identification, genetic mechanisms of disease, and functional assays for ATM and related proteins, including cellular responses to ioinizing radiation. Another project identifies therapeutic approaches to ATM based on specific groups of mutations.
* Hilary Godwin, Ph.D.
Environmental Health Sciences - Full BiographyDr. Godwin's research focuses on the basic chemical and biological mechanisms by which toxic metal ions affect neurological signaling and development and the mechanisms by which nanoparticles enter living systems and impact biological processes.
+* Oliver Hankinson, Ph.D.
Molecular Toxicology Ph.D. Program Director , and Department of Pathology and Laboratory Medicine - Full BiographyDr. Hankinson's research focuses on the mechanism of carcinogenesis by polycyclic aromatic hydrocarbons (found in cigarette smoke and smog) and dioxin (a widespread pollutant and related compounds, using molecular biology, cell culture and animal model systems.
Louis J. Ignarro, Ph.D.
Molecular and Medical Pharmacology - Full BiographyDr. Ignarro's research is directed toward elucidating mechanisms of regulation of nitric oxide (NO) production and cytotoxicity in macrophages, vascular cells, and tumor cells.
+* David Krantz, Ph.D
Psychiatry and Biobehavioral Sciences - Full BiographyDr. Krantz uses Drosophila to study how changes in the function of neurotransmitter transporters may influence synaptic transmission and behavior.
William McBride, Ph.D
Radiation Oncology - Full BiographyDr. McBride's research focuses on degradation of proteins through the proteasome system and the inhibitory effects of exposure to radiation, and other agents.
William Melega, Ph.D.
Molecular and Medical Pharmacology - Full BiographyDr. Melega studies the molecular mechanisms of neurodegenerative diseases and drug addiction.
* Sabeeha Merchant, Ph.D.
Chemistry and Biochemistry - Full BiographyDr. Merchant studies the biochemistry and molecular genetics of metal metabolism.
+ Jeffrey H. Miller, Ph.D.
MIMG - Full BiographyDr. Miller's group is interested in understanding how mutations occur in cells of bacteria, and how cells avoid mutagenesis with different repair strategies. We are also interested in understanding repair systems in humans, and how defects in these systems lead to cancer.
+ Andre Nel, MD, Ph.D.
Medicine - Full BiographyDr. Nel's research focuses on the adverse effects of particulate pollutants, including manufactured nanoparticles and diesel exhaust particles, to the lung.
Frank Pajonk, M.D., Ph.D
Radiation Oncology/Division of Molecular and Cellular Oncology - Full BiographyDr. Pajonk's research is focussed on radiation effects of the proteasome and cancer stem cells.
Suzanne E. Paulson, Ph.D.
Atmospheric Sciences - Full BiographyDr. Paulson's group is investigating generation of reactive oxygen species by ambient particulate matter, mapping air pollution in urban microenvironments, and investigating aerosol optical properties.
+* Beate Ritz, MD., Ph.D.
Epidemiology and Environmental Health - Full BiographyDr. Ritz's primary research interests are the effects of occupational and environmental toxins such as pesticides, ionizing radiation, and air pollution on chronic diseases including neurodegenerative disorders (Parkinson's disease), cancer, and adverse birth outcomes.
* Wendie Robbins, Ph.D.
Nursing/ Environmental Health Sciences - Full BiographyDr. Robbins' research focuses on the molecular mechanisms of environmentally induced germ cell genetic damage and the development of biomarkers to detect and measure this damage in human sperm cells
* Michael Roth, M.D
Medicine - Full BiographyDr. Roth's research focuses on the toxicology of inhaled substance abuse.
+* Robert Schiestl, Ph.D.
Pathology/ Environmental Health Sciences - Full BiographyDr. Schiestl's work centers mostly on basic mechanisms, genetic control, and inducibility by environmental carcinogens and nanoparticles of homologous and illegitimate recombination, which are molecular events involved in carcinogenesis.
Joan S. Valentine, Ph.D.
Chemistry and Biochemistry - Full BiographyDr. Valentine's research focuses on copper-zinc superoxide dismutase and Lou Gehrig's disease and on yeast studies of oxidative stress and antioxidants.
Xia Yang, Ph.D.
Integrative Biology and Physiology - Full BiographyDr. Yang's research focuses on identifying key regulatory genes and gene networks that mediate the effect of genetic and environmental perturbations on metabolic diseases using high-throughput genomic and computational approaches. Dr. Yang is also interested in applying similar approaches to pharmacogenomic and toxicogenomic studies to understand the genomic architecture of drug metabolism, drug response, and toxicity.
Zuo-Feng Zhang, Ph.D.
Epidemiology - Full BiographyDr. Zhang's research interests focus on molecular genetic epidemiology of cancers of the lung, bladder, prostate, esophagus, stomach, liver, head and neck cancer, cervix, and AIDS-related malignancies. His research team is working on the role of mutations, methylations, and polymorphisms of genes in the development of cancer. The major focus of his research group is to evaluate the main effects of these genes on the risk of cancers and to assess potential gene-environment interactions. Dr. Zhang is also interested in risk and protective factors for major cancers such as cancers of the lung, esophagus, stomach, and liver in Chinese population, nutrition and cancer, epidemiology of second primary cancers, methodological issues in the use of tumor markers in cancer epidemiology, and the application of tumor markers in progression and survival of cancer.